Cancer Imaging Phenomics Toolkit (CaPTk)  1.5.1
Non-invasive Imaging Biomarker of EGFRvIII in Glioblastoma Patients


Science_EGFRvIII.png
Distributions of the Imaging Biomarker (the φ index) by EGFRvIII expression status.

References:

  • S.Bakas, H.Akbari, J.Pisapia, M.Martinez-Lage, M.Rozycki, S.Rathore, N.Dahmane, D.M.O'Rourke, C.Davatzikos, "In vivo detection of EGFRvIII in glioblastoma via perfusion magnetic resonance imaging signature consistent with deep peritumoral infiltration: the phi-index", Clin Cancer Res. 23(16):4724-4734, 2017. DOI:10.1158/1078-0432.CCR-16-1871
  • S.Bakas, H.Akbari, J.Pisapia, M.Rozycki, D.M.O'Rourke, C.Davatzikos. "Identification of Imaging Signatures of the Epidermal Growth Factor Receptor Variant III (EGFRvIII) in Glioblastoma", Neuro Oncol. 17(Suppl 5):v154, 2015. DOI:10.1093/neuonc/nov225.05
  • S.Bakas, Z.A.Binder, H.Akbari, M.Martinez-Lage, M.Rozycki, J.J.D.Morrissette, N.Dahmane, D.M.O'Rourke, C.Davatzikos, "Highly-expressed wild-type EGFR and EGFRvIII mutant glioblastomas have similar MRI signature, consistent with deep peritumoral infiltration", Neuro Oncol. 18(Suppl 6):vi125-vi126, 2016. DOI:10.1093/neuonc/now212.523