Cancer Imaging Phenomics Toolkit (CaPTk)  1.4.0_Beta.s
Download Instructions

CaPTk is currently distributed in the form of pre-compiled (executable) Windows installer, and we are actively working on producing pre-compiled binaries for Linux and macOS machines too.

The Windows executable package (provided in the download link below) contains all required dependencies and does not need administrative privileges for installation. The Linux executable assumes Qt 4.8.x installed on the system and in the PATH and was built using GCC 4.8.6 (default with Ubuntu 14.04); the custom path for installation can be specified using the following command:

$package --target $desiredInstallDir

NOTE: For Ubuntu 16.04 users, please run following command after installing CaPTk:

sudo apt install libqtwebkit4

To download the CaPTk source code along with various sample datasets, please visit our Download Page hosted in NIH-supported NITRC.

Please cite at least one of the following publications when you use CaPTk in your research:

  • C.Davatzikos, S.Rathore, S.Bakas, S.Pati, M.Bergman, R.Kalarot, P.Sridharan, A.Gastounioti, N.Jahani, E.Cohen, H.Akbari, B.Tunc, J.Doshi, D.Parker, M.Hsieh, A.Sotiras, H.Li, Y.Ou, R.K.Doot, M.Bilello, Y.Fan, R.T.Shinohara, P.Yushkevich, R.Verma, D.Kontos, "Cancer imaging phenomics toolkit: quantitative imaging analytics for precision diagnostics and predictive modeling of clinical outcome", J Med Imaging, 5(1):011018, 2018 DOI: 10.1117/1.JMI.5.1.011018
  • S.Pati, S.Bakas, A.Sotiras, R.Kalarot, P.Sridharan, M.Bergman, S.Rathore, H.Akbari, P.Yushkevich, T.Shinohara, Y.Fan, D.Kontos, R.Verma, C.Davatzikos. "Cancer Imaging Phenomics Toolkit (CaPTk): A Radio(geno)mics Software Platform Leveraging Quantitative Imaging Analytics for Computational Oncology", 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), Nov.26–Dec.1, 2017, Chicago IL.
  • S.Pati, S.Rathore, R.Kalarot, P.Sridharan, M.Bergman, T.Shinohara, P.Yushkevich, Y.Fan, R.Verma, D.Kontos, C.Davatzikos. "Cancer and Phenomics Toolkit (CaPTk): A Software Suite for Computational Oncology and Radiomics", 102nd Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), Nov.27-Dec.2, 2016, Chicago IL.


By installing the CaPTk, the user agrees to the following licenses, which pertain to the code and its different constituents:

  1. SBIA Software License -
  2. SBIA Non-Commercial Software License -
  3. Insight Toolkit License -
  4. Visualization Toolkit License -
  5. Qt Open Source License -
  6. CC Attribution-ShareAlike for SRI24 data -
  7. MRIcroGL License - BSD

The CaPTk software family (which includes the interactive framework and available applications) incorporates 3rd party libraries and toolkits. All rights to these components are subject to the terms and licenses of their respective owners. All trademarks are the property of their respective owners.

The incorporated packages include but are not limited to:

  2. ITK, Insight Software Consortium, Apache 2.0 License
  3. VTK, Kitware, BSD License
  4. OpenCV, OpenCV, 3-Clause BSD License
  5. KernelFit, Geoffrey Lentner, GPLv3
  6. MATLAB Runtime, MathWorks, see MCR_license.txt within the Licenses folder of the CaPTk installation
  7. ITK-SNAP,Paul A. Yushkevich, Joseph Piven, Heather Cody Hazlett, Rachel Gimpel Smith, Sean Ho, James C. Gee, and Guido Gerig. User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability. Neuroimage 2006 Jul 1;31(3):1116-28, GPLv3

Changelog (Release notes)


  • Performance and UI improvements


  • Labels updated to support GLISTR and GLISTRboost outputs
  • Added a way to invoke CaPTk from the command line to make QC of multiple subjects easier
  • Double click to add tissue points and tumor point centers
  • New applications added
  • Performance and UI improvements


  • New applications added
  • Interactive functionality updated
  • Added central core for statistical analyses
  • Bug fixes


  • Added functionality to drawing
  • Documentation updated with more illustrative screenshots


  • Updated documentation outside and inside the application
  • Random bug-fixes


  • First public release of CaPTk_Full (version 1.0.0)
  • Applications populated using highlighted algorithms from CBICA
  • Feature Panel added to generate a comprehensive radiomic feature set for training
  • More optimizations and bug-fixes in interaction


  • Release for MICCAI 2016
  • UI optimizations
  • Seed point selector updated


  • Move to a date-based versioning system for more clarity and coherence
  • SeedSelector version for GLISTR, GLISTRboost, PORTR added to compilation
  • Major UI overhaul with more dynamic elements


  • Bug fixes in the seed points are saved
  • Generic interactive improvements


  • First (internal) release of CaPTk
  • Mostly a prototype at this stage
  • Interactive elements (seed-point initialization, ROI drawing) work properly
  • Image loading for NIfTI and DICOM works
  • Some applications have been added to the compilation for testing

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